Selank/Semax
$85.00
For research use only. Selank and Semax are synthetic neuropeptide analogs derived from tuftsin and ACTH(4-7) respectively, supplied together for comparative laboratory research in central nervous system signaling and neuropeptide activity.
| FORM | PURITY |
|---|---|
| Lyophilized Powder | ≥99% (HPLC) |
Selank/Semax For Laboratory Research
For In Vitro Research Use Only – Not for Human or Veterinary Application
Selank is a synthetic heptapeptide analog of the endogenous immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg), with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. It has been studied in laboratory settings for its interaction with the GABAergic system and its reported influence on brain-derived neurotrophic factor (BDNF) expression in in vitro models.
Semax is a synthetic analog of the ACTH(4-7) fragment, with the sequence Met-Glu-His-Phe-Pro-Gly-Pro. Research has examined its neuroprotective properties in cellular models, its interaction with BDNF and NGF signaling pathways, and its activity at melanocortin receptors. Both peptides have been subjects of scientific inquiry in Russia and internationally, with published research exploring their behavioral and neurochemical effects in controlled preclinical models.
Together, Selank and Semax represent distinct but complementary research tools for investigating neuropeptide signaling and CNS pathway modulation. Tested in the USA for research and educational use.
Compound Details
| Selank Full Name | L-Threonyl-L-Lysyl-L-Prolyl-L-Arginyl-L-Prolylglycyl-L-Proline (TKPRPGP) |
| Selank CAS | 129954-34-3 |
| Selank MW | 751.9 g/mol |
| Semax Full Name | Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP) · ACTH(4-10) analog |
| Semax CAS | 80714-61-0 |
| Semax MW | 813.9 g/mol |
| Purity | ≥99% by HPLC (each component) |
| Appearance | White lyophilized powder |
| Solubility | Sterile water or bacteriostatic water |
| Storage | −20°C long-term; 4°C short-term (≤4 weeks lyophilized); use reconstituted solution within 14–28 days |
| For Use | Laboratory and in vitro research purposes only |
Public Research References
Published Research References
- Dolotov OV, Karpenko EA, Inozemtseva LS, et al. Semax, an analogue of ACTH(4-10), regulates BDNF and trkB expression in the rat hippocampus. Brain Res. 2006;1117(1):54–60. PMID: 16959221 →
- Medvedeva EV, Dmitrieva VG, Povarova OV, et al. The peptide Semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia. BMC Neurosci. 2014;15:128. PMID: 25406907 →
- Pavlov TS, et al. Peptides Semax and Selank affect the behavior of rats with 6-OHDA induced PD-like parkinsonism. Dokl Biol Sci. 2017;475(1):131–134. PMID: 28702721 →
- Semenova TP, Kozlovskaya MM, Zuikov AV, Kulikov AV. Effects of Selank on neurochemical and behavioral parameters in animal models. Bull Exp Biol Med. 2010;150(3):351–354. Citation only — limited PubMed indexing.
- Kaplan AY, Kochetova AG, Nezavibathko VN, et al. Synthetic ACTH analogue Semax displays nootropic-like activity in humans. Neurosci Res Commun. 1996;19:115–123. Citation only — limited PubMed indexing.
All references are provided for informational purposes. Products are for laboratory and scientific research purposes only. Not for human or animal consumption.
RESEARCH USE ONLY
All products sold by Hive Mind Peptides are intended strictly for laboratory and scientific research purposes only. These materials are not approved by the FDA and are not intended for human or veterinary use, clinical applications, diagnostic procedures, or therapeutic treatment of any kind. You must be 21 years of age or older to purchase.
By purchasing from Hive Mind Peptides, you confirm that you are a qualified researcher and that all materials will be handled solely within an appropriate research environment by personnel who understand the risks, limitations, and regulatory requirements associated with investigational compounds. Products must not be administered to humans or animals, represented as therapeutic agents, or used for any medical purpose.
Use of these materials is entirely at your own risk. Hive Mind Peptides assumes no liability for misuse, unsafe handling, improper application, or any regulatory or compliance issues arising from their use.
